Pre-Diabetes/Type II Diabetes and Obesity Study

We are recruiting overweight and obese participants with prediabetes or metformin-treated Type 2 Diabetes for a clinical research study investigating a product in capsule, Gelesis200.

If you would like to participate in a clinical research study testing the effect of Gelesis200, where you will receive dietary counselling for a weight loss, we would like to hear from you.

Gelesis200, administered in capsules, contains two natural food ingredients. The study is investigating if capsules containing Gelesis200 can promote your weight loss. The capsules should be ingested daily before breakfast, lunch, and dinner.

We are looking for overweight and obese women and men, with untreated prediabetes or metformin-treated Type 2 Diabetes. In order to participate, you should at least fulfill the following criteria:

• Age: 22 – 65 years
• BMI between 27 and 40 kg/m2
• Weigh less than 120 kg (264 pounds)
• Generally healthy with the exception of overweight/obesity, prediabetes and metformin-treated Type 2 Diabetes

You cannot participate in the study, if you for example:
• Have had obesity surgery
• Have an eating disorder
• Have a gastrointestinal disorder
• Are pregnant or lactating or planning pregnancy within the next 8 months

If you would like to participate, the study staff and doctor will take you through a screening process in order to assess if you fulfill all criteria for participating in the study.

The study will last up to 31 weeks and consist of 15 visits, to include physical examinations and blood samplings conducted at our research center. The study product should be ingested three times daily for 24 weeks. During the study, several questionnaires should be completed either during the visits or at home. You will receive capsules containing either Gelesis200 or inactive ingredient (placebo). The product you will receive during the study is assigned to you randomly (by chance, like the flip of a coin). Both you and the clinical personnel involved in the study will be blinded to the product you receive during the entire study.

All assessments, dietary counselling, and study products are free. Compensation up to $1275 may be available for time and travel.

To learn if you might qualify, please complete the brief questionnaire for this study or contact a member of our recruitment team by calling 865-305-DRUG(3784).