About Us

Now an Integrated Site Network of AMR!

The Alliance for Multispeciality Research (AMR) is a unique network of integrated  geographically diverse, and highly experienced Clinical Research Centers of Excellence. Chartered as a formal organization in 1994, AMR Centers of Excellence provide clinical trial services across a broad base of therapeutic areas to the pharmaceutical, biotechnology, nutrition and medical device industries.

To learn more about AMR’s fully integrated network click here:  amrllc.com


Established in New Orleans in 1985, NOCCR still maintains the original Canal Street location. Following Hurricane Katrina, the Phase I unit and company headquarters were moved to Knoxville, TN.

NOCCR Knoxville and Volunteer Research Group are headquartered inside East Tennessee’s premier research hospital; ideally located for complex clinical trials.

Knoxville Site

Knoxville, TN Senior Management

(Pictured from left to right: Richard L. Gibson MD, Sandra Gibson RN MBA, William B. Smith MD, and Nyda Brook JD)

William B. Smith, MD, FACC, is the Founder, President, and Principal Investigator. He is board certified in Internal Medicine, Critical Care Medicine, Nephrology, and Cardiology. He has been involved in greater than 1500 clinical trials over the past 35 years. Dr. Smith is a frequent lecturer and author and publishes extensively in clinical and scientific journals.

Richard L. Gibson, MD, is a Principal Investigator and has been with NOCCR for 10 years. He is board certified in Internal Medicine, Nephrology, Psychiatry, and Forensic Psychiatry, and MPH in Tropical Medicine.

Nyda Brook, JD, Vice President and General Counsel, has been with NOCCR since 1999. Prior to joining our team, she practiced healthcare law in New Orleans.

Sandra Gibson, RN, MBA, Vice President and Operations Director, has been with NOCCR since 1999. Sandy is certified in Nephrology and Critical Care Nursing as well as clinical research coordination.

Business Development

Amy Rushing –  Amy joined VRG/NOCCR in 2004 and has worked in various capacities with the company. She currently works in Business Development and Regulatory Services. Please connect with her via LinkedIn, email at arushing@noccr.com, or phone at (865)305-9100 ext. 234.

Professional Clinical Staff

We have experienced medical staff on duty at the facilities 24/7 including 12 full-time study coordinators, 2 full-time Nurse Practitioners, 20 coordinator assistants, IATA certified lab coordinators, and contract and budget specialists. Our coordinators each have an average of 6 years’ experience in the medical field.


dr ramon vargasDr. Ramon Vargas, MD, has been a principle investigator for more than thirty years, including seven years with NOCCR. He is board certified in Clinical Pharmacology, and holds an MPH in tropical Medicine.